Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activatedBy |
gptkb:p38_MAP_kinase
|
| gptkbp:alternativeName |
gptkb:MAPKAPK2
MK2 |
| gptkbp:discoveredBy |
Johannes L. Bos group
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:EC_number |
2.7.11.1
|
| gptkbp:encodedBy |
MAPKAPK2 gene
|
| gptkbp:function |
regulates stress and inflammatory responses
phosphorylates heat shock protein HSP27 |
| https://www.w3.org/2000/01/rdf-schema#label |
MAPKAP kinase 2
|
| gptkbp:involvedIn |
cellular response to stress
inflammatory signaling pathway |
| gptkbp:locatedOnChromosome |
1q32
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
45 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:CREB
gptkb:SRF gptkb:HSPB1 LSP1 |
| gptkbp:regulates |
cytokine production
mRNA stability |
| gptkbp:UniProtID |
P49137
|
| gptkbp:bfsParent |
gptkb:MAPKAPK2
gptkb:PRKMK2 |
| gptkbp:bfsLayer |
7
|