Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:HPK1
MAPK/ERK kinase kinase kinase 1 |
| gptkbp:alternativeName |
gptkb:HPK1
|
| gptkbp:associatedWith |
immune response
|
| gptkbp:discoveredBy |
1996
|
| gptkbp:encodes |
gptkb:Mitogen-activated_protein_kinase_kinase_kinase_kinase_1
|
| gptkbp:Entrez_Gene_ID |
11184
ENSG00000104880 |
| gptkbp:expressedIn |
hematopoietic cells
|
| gptkbp:function |
protein serine/threonine kinase activity
involved in T-cell signaling |
| gptkbp:HGNC_ID |
HGNC:6857
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP4K1 gene
|
| gptkbp:locatedOnChromosome |
19
19q13.1 |
| gptkbp:mutationAssociatedWith |
gptkb:cancer
autoimmune diseases |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Map4k1
|
| gptkbp:pathway |
gptkb:T_cell_receptor_signaling_pathway
gptkb:MAPK_signaling_pathway |
| gptkbp:product |
HPK1 protein
|
| gptkbp:regulates |
gptkb:JNK_pathway
NF-kappaB activity |
| gptkbp:UniProtID |
Q92918
|
| gptkbp:bfsParent |
gptkb:Hematopoietic_Progenitor_Kinase
|
| gptkbp:bfsLayer |
7
|