Lymphoid Enhancer-binding Factor
GPTKB entity
Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:LEF
|
gptkbp:associatedWith |
gptkb:cancer
|
gptkbp:binds |
gptkb:gene
|
gptkbp:contains |
HMG-box domain
|
gptkbp:discoveredIn |
1990s
|
gptkbp:expressedIn |
lymphoid cells
|
gptkbp:foundIn |
vertebrates
|
gptkbp:function |
transcription factor
|
gptkbp:gene |
gptkb:LEF1
|
https://www.w3.org/2000/01/rdf-schema#label |
Lymphoid Enhancer-binding Factor
|
gptkbp:interactsWith |
gptkb:beta-catenin
|
gptkbp:involvedIn |
gptkb:Wnt_signaling_pathway
|
gptkbp:locatedOnChromosome |
chromosome 4 (human LEF1)
|
gptkbp:memberOf |
gptkb:TCF/LEF_family
|
gptkbp:orthologIn |
mouse Lef1
zebrafish lef1 |
gptkbp:regulates |
cell differentiation
cell proliferation gene expression T-cell development |
gptkbp:bfsParent |
gptkb:LEF
|
gptkbp:bfsLayer |
7
|