Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cardiovascular_disease
tooth development bone density regulation |
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodes |
LRP6 protein
|
| gptkbp:Entrez_Gene_ID |
4040
ENSG00000134970 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
gptkb:Low-density_lipoprotein_receptor-related_protein_6
|
| gptkbp:function |
co-receptor in Wnt signaling pathway
|
| gptkbp:HGNC_ID |
6698
|
| https://www.w3.org/2000/01/rdf-schema#label |
Lrp6
|
| gptkbp:interactsWith |
gptkb:Frizzled_receptors
gptkb:Wnt_proteins |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12
12p13.2 |
| gptkbp:mutationAssociatedWith |
can cause familial tooth agenesis
can increase risk of coronary artery disease |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Lrp6
|
| gptkbp:proteinFamily |
gptkb:LDL_receptor_family
|
| gptkbp:relatedTo |
gptkb:Wnt_signaling_pathway
|
| gptkbp:UniProtID |
O75581
|
| gptkbp:bfsParent |
gptkb:LRP6
|
| gptkbp:bfsLayer |
8
|