Low-density lipoprotein receptor-related protein 6
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:LRP6
|
| gptkbp:alternativeName |
Arrow (in Drosophila)
|
| gptkbp:discoveredIn |
1998
|
| gptkbp:domain |
EGF-like domain
LDL-receptor class A repeat YWTD repeat |
| gptkbp:encodedBy |
gptkb:LRP6_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
co-receptor in Wnt signaling pathway
|
| https://www.w3.org/2000/01/rdf-schema#label |
Low-density lipoprotein receptor-related protein 6
|
| gptkbp:involvedIn |
embryonic development
cell signaling bone formation |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12p13.2
|
| gptkbp:location |
gptkb:plasma_membrane
|
| gptkbp:molecularWeight |
161 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:bone
coronary artery disease |
| gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Mus_musculus |
| gptkbp:relatedTo |
gptkb:Low-density_lipoprotein_receptor-related_protein_5
|
| gptkbp:UniProtID |
O75581
|
| gptkbp:bfsParent |
gptkb:LRP6
|
| gptkbp:bfsLayer |
8
|