|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RBTN2
gptkb:Rhombotin-2
gptkb:TTG2
|
|
gptkbp:associatedWith
|
gptkb:T-cell_acute_lymphoblastic_leukemia
|
|
gptkbp:discoveredBy
|
T. Boehm et al.
|
|
gptkbp:discoveredIn
|
1991
|
|
gptkbp:domain
|
gptkb:LIM_domain
|
|
gptkbp:encodes
|
gptkb:LIM_domain_only_protein_2
|
|
gptkbp:Entrez_Gene_ID
|
4005
ENSG00000142747
|
|
gptkbp:expressedIn
|
hematopoietic stem cells
|
|
gptkbp:fullName
|
gptkb:LIM_domain_only_2
|
|
gptkbp:function
|
transcriptional regulator
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPseudogene
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lmo2
|
|
gptkbp:interactsWith
|
gptkb:GATA1
gptkb:TAL1
gptkb:E47
gptkb:LDB1
|
|
gptkbp:involvedIn
|
hematopoiesis
|
|
gptkbp:length
|
2 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p13
|
|
gptkbp:mouseKnockoutPhenotype
|
embryonic lethality due to failure of blood vessel formation
|
|
gptkbp:mutationAssociatedWith
|
leukemia
|
|
gptkbp:OMIM
|
180385
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Lmo2
|
|
gptkbp:proteinFamily
|
gptkb:LIM-only_proteins
|
|
gptkbp:regulates
|
transcription of erythroid genes
|
|
gptkbp:significance
|
tumor suppressor
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
P25791
|
|
gptkbp:usedIn
|
gene therapy research
|
|
gptkbp:bfsParent
|
gptkb:LMO2
|
|
gptkbp:bfsLayer
|
7
|