T-cell acute lymphoblastic leukemia
GPTKB entity
Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:T-cell_ALL
|
| gptkbp:affects |
T-cells
|
| gptkbp:age |
gptkb:Person
young adults |
| gptkbp:can_lead_to |
bone marrow failure
|
| gptkbp:clinical_trial |
gptkb:vaccine
ongoing research new therapies |
| gptkbp:current_use |
lymphadenopathy
hepatomegaly splenomegaly |
| gptkbp:end_of_life |
varies by risk group
improving with new treatments |
| gptkbp:events |
psychosocial support
regular check-ups monitoring for relapse |
| gptkbp:genetic_diversity |
gptkb:PTEN
t(5;14)(q35;q32) FBX W7 NOTC H1 |
| https://www.w3.org/2000/01/rdf-schema#label |
T-cell acute lymphoblastic leukemia
|
| gptkbp:is_characterized_by |
rapid proliferation of lymphoblasts
|
| gptkbp:is_often_used_in |
gptkb:Person
females males |
| gptkbp:is_used_for |
fatigue
fever bleeding easy bruising pallor |
| gptkbp:occurs_in |
higher in African American children
higher in Hispanic children |
| gptkbp:research_focus |
biomarkers
targeted therapies genetic profiling |
| gptkbp:risk_factor |
genetic disorders
chemical exposure exposure to radiation |
| gptkbp:side_effect |
nausea
hair loss increased risk of infection |
| gptkbp:social_responsibility |
blood tests
varies by age bone marrow biopsy varies by treatment response |
| gptkbp:symptoms |
fatigue
weight loss fever easy bruising |
| gptkbp:treatment |
gptkb:drug
radiation therapy chemotherapy remission stem cell transplant |
| gptkbp:type_of |
gptkb:early_T-cell_precursor_leukemia
cortical T-cell leukemia mature T-cell leukemia |