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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD91
|
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gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
atherosclerosis
|
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gptkbp:domain
|
EGF-like domain
ligand-binding domain
beta-propeller domain
|
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gptkbp:expressedIn
|
brain
liver
macrophages
smooth muscle cells
|
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gptkbp:fullName
|
gptkb:Low-density_lipoprotein_receptor-related_protein_1
|
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gptkbp:function
|
cell signaling
endocytosis
|
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gptkbp:gene
|
LRP1 gene
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LRP1 protein
|
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gptkbp:interactsWith
|
gptkb:tissue_plasminogen_activator
gptkb:Apolipoprotein_E
gptkb:alpha-2-macroglobulin
gptkb:amyloid_precursor_protein
|
|
gptkbp:involvedIn
|
lipoprotein metabolism
clearance of apoptotic cells
regulation of protease activity
|
|
gptkbp:locatedOnChromosome
|
12q13.3
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~600 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:subunit
|
alpha chain
beta chain
|
|
gptkbp:UniProtID
|
gptkb:Q07954
|
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gptkbp:bfsParent
|
gptkb:LRP1
|
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gptkbp:bfsLayer
|
7
|