|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:ligand-gated_ionotropic_receptor
ionotropic receptor
|
|
gptkbp:foundIn
|
animals
plants
prokaryotes
|
|
gptkbp:fullName
|
gptkb:Ligand-Gated_Ion_Channel_family
|
|
gptkbp:function
|
mediate fast synaptic transmission
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LGIC family
|
|
gptkbp:includes
|
gptkb:glutamate_receptor
gptkb:GABA_A_receptor
gptkb:glycine_receptor
gptkb:serotonin_5-HT3_receptor
nicotinic acetylcholine receptor
|
|
gptkbp:mechanismOfAction
|
open ion channel in response to ligand binding
|
|
gptkbp:memberOf
|
gptkb:ion_channel_superfamily
|
|
gptkbp:mutationAssociatedWith
|
neurological disorders
|
|
gptkbp:regulates
|
neuronal excitability
membrane potential
|
|
gptkbp:relatedTo
|
gptkb:synaptic_plasticity
central nervous system
neurotransmission
|
|
gptkbp:structure
|
transmembrane protein
|
|
gptkbp:studiedIn
|
neuroscience
|
|
gptkbp:subunit
|
multiple subunits
|
|
gptkbp:target
|
pharmacological agents
|
|
gptkbp:bfsParent
|
gptkb:Cys-loop_receptor_family
|
|
gptkbp:bfsLayer
|
6
|