Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:ion_channel |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
hyperekplexia
|
| gptkbp:discoveredBy |
1970s
|
| gptkbp:EC_number |
none (not an enzyme)
|
| gptkbp:encodedBy |
gptkb:GLRA1
gptkb:GLRA2 gptkb:GLRA3 gptkb:GLRA4 gptkb:GLRB |
| gptkbp:enemyOf |
gptkb:strychnine
glycine |
| gptkbp:expressedIn |
gptkb:spinal_cord
retina brainstem |
| gptkbp:foundIn |
central nervous system
|
| gptkbp:function |
mediates inhibitory neurotransmission
|
| gptkbp:GO_term |
GO:0004890
|
| gptkbp:inhibitedBy |
neuronal firing
|
| gptkbp:ligand |
glycine
|
| gptkbp:location |
postsynaptic membrane
|
| gptkbp:modulatedBy |
zinc
|
| gptkbp:OMIM |
138491
|
| gptkbp:permeableTo |
chloride ions
|
| gptkbp:structure |
pentameric
|
| gptkbp:subunit |
alpha subunit
beta subunit |
| gptkbp:targetOfDrug |
anesthetics
muscle relaxants |
| gptkbp:UniProtID |
P23415
|
| gptkbp:bfsParent |
gptkb:Cys-loop_receptor_family
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
glycine receptor
|