|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:WBSCR5
gptkb:WSCR5
pp36
|
|
gptkbp:associatedWith
|
gptkb:immunodeficiency_52
|
|
gptkbp:discoveredBy
|
Weiss A et al.
|
|
gptkbp:encodes
|
gptkb:Linker_for_activation_of_T_cells_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000115041
27040
|
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gptkbp:expressedIn
|
gptkb:T_cells
|
|
gptkbp:firstDescribed
|
1998
|
|
gptkbp:fullName
|
gptkb:Linker_for_activation_of_T_cells
|
|
gptkbp:function
|
adaptor protein in T-cell receptor signaling
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:6521
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LAT (gene)
|
|
gptkbp:interactsWith
|
gptkb:Grb2
gptkb:PLCĪ³1
gptkb:ZAP-70
gptkb:SLP-76
gptkb:Gads
|
|
gptkbp:length
|
262 amino acids
|
|
gptkbp:locatedOnChromosome
|
16
|
|
gptkbp:location
|
16q24.1
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
impaired T cell development
|
|
gptkbp:OMIM
|
602805
|
|
gptkbp:pathway
|
gptkb:T_cell_receptor_signaling_pathway
immune response
|
|
gptkbp:phosphorylates
|
multiple tyrosine residues
|
|
gptkbp:protein_function
|
scaffold for assembly of signaling complexes
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:UniProtID
|
O43561
|
|
gptkbp:bfsParent
|
gptkb:LAT
|
|
gptkbp:bfsLayer
|
6
|