|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CD305
Leukocyte immunoglobulin-like receptor subfamily B member 4
hLAIR1
|
|
gptkbp:associatedWith
|
autoimmune diseases
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:domain
|
immunoglobulin-like domain
|
|
gptkbp:downregulated_in
|
some cancers
|
|
gptkbp:Entrez_Gene_ID
|
3903
ENSG00000167618
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
gptkb:NK_cells
gptkb:B_cells
gptkb:T_cells
dendritic cells
monocytes
|
|
gptkbp:foundIn
|
gptkb:cell_membrane
|
|
gptkbp:fullName
|
gptkb:Leukocyte-associated_immunoglobulin-like_receptor_1
|
|
gptkbp:function
|
inhibitory receptor on immune cells
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:6527
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
LAIR1
|
|
gptkbp:inhibitedBy
|
cytokine production
immune cell activation
|
|
gptkbp:interactsWith
|
collagen
|
|
gptkbp:length
|
287
|
|
gptkbp:locatedOnChromosome
|
19q13.4
chr19: 54,837,964-54,841,070
|
|
gptkbp:molecularWeight
|
32 kDa
|
|
gptkbp:motif
|
ITIM (Immunoreceptor Tyrosine-based Inhibitory Motif)
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Lair1
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:regulates
|
immune response
inflammatory response
|
|
gptkbp:signalPeptide
|
present
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
Q6GTX8
|
|
gptkbp:bfsParent
|
gptkb:CD305
|
|
gptkbp:bfsLayer
|
8
|