Kaposi's sarcoma-associated herpesvirus
GPTKB entity
Statements (87)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:virus
|
| gptkbp:bfsLayer |
3
|
| gptkbp:bfsParent |
gptkb:healthcare_organization
|
| gptkbp:associated_with |
gptkb:primary_effusion_lymphoma
gptkb:classic_Kaposi's_sarcoma gptkb:endemic_Kaposi's_sarcoma gptkb:HIV/_AIDS gptkb:castle chronic inflammation lymphatic system immunosuppression tumor angiogenesis HIV-positive individuals immune evasion transplant recipients lymphoproliferative disorders vascular lesions viral latency viral reactivation epidemic Kaposi's sarcoma iatrogenic Kaposi's sarcoma cytokine dysregulation |
| gptkbp:belongs_to |
gptkb:Herpesviridae
Herpesviridae family |
| gptkbp:catch_rate |
establishes latency in B cells
reactivates in immunocompromised hosts |
| gptkbp:caused_by |
gptkb:healthcare_organization
|
| gptkbp:clinical_trial |
ongoing for new treatments
|
| gptkbp:discovered_by |
gptkb:Yoshihiro_K._Nishimura
gptkb:1994 |
| gptkbp:family |
gptkb:Herpesviridae
|
| gptkbp:first_flight |
enveloped virus
|
| gptkbp:genetic_diversity |
gptkb:DJ
circular DNA |
| gptkbp:genus |
gptkb:Rhadinovirus
|
| gptkbp:healthcare |
in transplant recipients
in HIV-positive populations in regions with high HIV prevalence |
| https://www.w3.org/2000/01/rdf-schema#label |
Kaposi's sarcoma-associated herpesvirus
|
| gptkbp:is_found_in |
human hosts
|
| gptkbp:is_known_for |
gptkb:KSHV
Human herpesvirus 8 (HHV-8) |
| gptkbp:is_popular_in |
higher in immunocompromised individuals
|
| gptkbp:is_protected_by |
safe sex practices
screening for HIV screening in high-risk populations |
| gptkbp:is_recognized_by |
patients with Kaposi's sarcoma
|
| gptkbp:nutritional_value |
gptkb:LANA-1
v Bcl-2 v GPCR v IL-6 |
| gptkbp:origin |
B cells
endothelial cells monocytes |
| gptkbp:publishes |
gptkb:physicist
|
| gptkbp:related_to |
other herpesviruses
|
| gptkbp:research_focus |
immune response
antiviral drug development treatment strategies viral oncogenesis developing vaccines understanding pathogenesis |
| gptkbp:seed_dispersal |
double-stranded DNA
|
| gptkbp:size |
approximately 125 kb
|
| gptkbp:social_responsibility |
gptkb:multicentric_Castleman_disease
gptkb:primary_effusion_lymphoma biopsy serological tests PCR testing endemic in sub-Saharan Africa more common in immunocompromised individuals associated with transplant patients associated with Mediterranean populations |
| gptkbp:symptoms |
internal lesions
lesions in mucous membranes lesions on the skin |
| gptkbp:transmission |
organ transplantation
sexual contact blood transfusion |
| gptkbp:treatment |
gptkb:hospital
gptkb:vaccine radiation therapy chemotherapy antiviral therapy studying combination therapies exploring targeted therapies investigating immune therapies |