ORF50 (RTA)

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy viral lytic cycle
gptkbp:alternativeName gptkb:RTA
gptkbp:biologicalProcess DNA binding
transcription factor activity
gptkbp:discoveredIn 1998
gptkbp:encodedBy gptkb:Kaposi's_sarcoma-associated_herpesvirus
gptkbp:fullName Replication and Transcription Activator
gptkbp:function transcriptional activator
gptkbp:gene ORF50
https://www.w3.org/2000/01/rdf-schema#label ORF50 (RTA)
gptkbp:interactsWith host transcription machinery
viral promoters
gptkbp:locale gptkb:nucleus
gptkbp:locatedOnChromosome KSHV genome
gptkbp:organism gptkb:Human_herpesvirus_8
gptkbp:postTranslationalModification phosphorylation
sumoylation
gptkbp:regulates KSHV lytic gene expression
lytic gene expression
gptkbp:requires reactivation from latency
gptkbp:roleInVirus lytic replication switch protein
gptkbp:bfsParent gptkb:Kaposi's_sarcoma-associated_herpesvirus
gptkbp:bfsLayer 6