KSHV

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:abbreviation gptkb:HHV-8
gptkbp:alsoKnownAs gptkb:Human_herpesvirus_8
gptkbp:associatedWith gptkb:Kaposi's_sarcoma
gptkb:Multicentric_Castleman's_disease
gptkb:Primary_effusion_lymphoma
gptkbp:Baltimore_classification Group I (dsDNA viruses)
gptkbp:caps icosahedral
gptkbp:category human virus
oncovirus
gptkbp:discoveredBy gptkb:Patrick_S._Moore
gptkb:Yuan_Chang
gptkbp:discoveredIn 1994
gptkbp:encodes gptkb:K15_protein
gptkb:K1_protein
gptkb:LANA-1
gptkb:vFLIP
gptkb:vGPCR
gptkb:vIL-6
viral cyclin
gptkbp:enveloped true
gptkbp:family gptkb:Herpesviridae
gptkbp:fullName gptkb:Kaposi's_sarcoma-associated_herpesvirus
gptkbp:genomeSize ~165 kilobase pairs
gptkbp:genomeType double-stranded DNA
gptkbp:genus gptkb:Rhadinovirus
gptkbp:hostedBy gptkb:human
https://www.w3.org/2000/01/rdf-schema#label KSHV
gptkbp:latency gptkb:B_cells
endothelial cells
monocytes
gptkbp:NucleicAcid gptkb:gene
gptkbp:oncogenic true
gptkbp:order gptkb:Herpesvirales
gptkbp:prevalence higher in Mediterranean region
higher in men who have sex with men
higher in sub-Saharan Africa
gptkbp:primaryTargetCells gptkb:B_lymphocytes
endothelial cells
gptkbp:relatedTo gptkb:Epstein-Barr_virus
gptkbp:replicationSite gptkb:nucleus
gptkbp:structure enveloped icosahedral capsid
gptkbp:subfamily gptkb:Gammaherpesvirinae
gptkbp:transmissionRoute organ transplantation
blood transfusion
sexual contact
saliva
gptkbp:treatment antiviral drugs (limited efficacy)
chemotherapy (for associated cancers)
immunotherapy (for associated cancers)
gptkbp:vaccineAvailable false
gptkbp:bfsParent gptkb:Shreveport_Regional_Airport
gptkb:Kaposi's_sarcoma-associated_herpesvirus
gptkb:human_herpesvirus_8
gptkbp:bfsLayer 6