Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:EZH2
gptkb:Enhancer_of_zeste_homolog_2 |
| gptkbp:associatedWith |
gptkb:cancer
gene silencing |
| gptkbp:catalyzes |
trimethylation of histone H3 at lysine 27 (H3K27me3)
|
| gptkbp:component |
gptkb:nucleus
gptkb:Polycomb_Repressive_Complex_2_(PRC2) |
| gptkbp:encodedBy |
gptkb:EZH2_gene
|
| gptkbp:function |
histone methyltransferase
histone-lysine N-methyltransferase activity |
| gptkbp:GOProcess |
chromatin modification
|
| https://www.w3.org/2000/01/rdf-schema#label |
KMT6
|
| gptkbp:inhibitedBy |
gptkb:Tazemetostat
gptkb:GSK126 |
| gptkbp:locatedOnChromosome |
7q36.1
|
| gptkbp:molecularWeight |
~85 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Weaver_syndrome
various cancers |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:UniProtID |
gptkb:Q15910
|
| gptkbp:bfsParent |
gptkb:EZH2
|
| gptkbp:bfsLayer |
7
|