|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BTEB2
gptkb:IKLF
CKLF
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
prostate cancer
|
|
gptkbp:discoveredBy
|
Yoshikazu Nakamura
|
|
gptkbp:encodes
|
KLF5 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000102554
688
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:prostate
bladder
intestine
epithelial tissues
|
|
gptkbp:firstDescribed
|
1998
|
|
gptkbp:fullName
|
Kruppel-like factor 5
|
|
gptkbp:function
|
regulation of apoptosis
regulation of cell proliferation
transcription factor
regulation of differentiation
|
|
gptkbp:GO_term
|
GO:0003700
GO:0006355
|
|
gptkbp:HGNC_ID
|
HGNC:6350
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KLF5 gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_13
gptkb:13q22.1
|
|
gptkbp:MIM_number
|
604235
|
|
gptkbp:mutationAssociatedWith
|
oncogenic potential
tumor suppressor in some contexts
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Klf5
rat Klf5
|
|
gptkbp:proteinFamily
|
gptkb:Kruppel-like_factors
|
|
gptkbp:regulates
|
gptkb:EGF
gptkb:p53
gptkb:TGF-beta
gptkb:Wnt_signaling
cell cycle
stem cell maintenance
inflammatory response
epithelial cell growth
miRNAs
|
|
gptkbp:UniProtID
|
gptkb:Q13887
|
|
gptkbp:bfsParent
|
gptkb:KLF5
|
|
gptkbp:bfsLayer
|
8
|