|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:RAC
gptkb:PKB
gptkb:CWS6
gptkb:PKB_alpha
PRKBA
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Cowden_syndrome
gptkb:Proteus_syndrome
colorectal cancer
pancreatic cancer
|
|
gptkbp:EC_number
|
2.7.11.1
|
|
gptkbp:encodes
|
gptkb:RAC-alpha_serine/threonine-protein_kinase
|
|
gptkbp:Entrez_Gene_ID
|
207
ENSG00000142208
|
|
gptkbp:gene
|
gptkb:AKT1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasMIMNumber
|
164730
|
|
gptkbp:hasRefSeqID
|
NM_005163
|
|
gptkbp:HGNC_ID
|
391
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KEGG hsa:567
|
|
gptkbp:involves
|
gptkb:mTOR_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:FoxO_signaling_pathway
gptkb:Insulin_signaling_pathway
Apoptosis
Cell cycle
|
|
gptkbp:isKinase
|
true
|
|
gptkbp:isOncogene
|
true
|
|
gptkbp:length
|
480 amino acids
|
|
gptkbp:locatedOnChromosome
|
14
14q32.33
|
|
gptkbp:molecularWeight
|
56 kDa
|
|
gptkbp:OMIM
|
164730
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1UNQ
gptkb:3O96
4EJN
3MVH
3QKK
4EKL
4GV1
4GV2
4GV3
4GV4
4GV5
4GV6
4GV7
4GV8
4GV9
4GVA
4GVB
4GVC
4GVD
4GVE
4GVF
4GVG
4GVH
4GVI
4GVJ
4GVK
4GVL
4GVM
4GVN
4GVO
4GVP
4GVQ
4GVR
4GVS
4GVT
4GVU
4GVV
4GVW
4GVX
4GVY
4GVZ
|
|
gptkbp:UniProtID
|
gptkb:P31749
|
|
gptkbp:bfsParent
|
gptkb:P0CG47
|
|
gptkbp:bfsLayer
|
7
|