Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:TRIM28
TIF1β |
| gptkbp:associatedWith |
gptkb:cancer
epigenetic regulation |
| gptkbp:discoveredBy |
Friedrich M. Uckun et al.
|
| gptkbp:domain |
gptkb:bromodomain
RING finger domain B-box domain coiled-coil domain PHD finger |
| gptkbp:encodedBy |
TRIM28 gene
|
| gptkbp:firstDescribed |
1996
|
| gptkbp:function |
chromatin remodeling
transcriptional corepressor |
| gptkbp:gene |
gptkb:TRIM28
|
| https://www.w3.org/2000/01/rdf-schema#label |
KAP1
|
| gptkbp:interactsWith |
gptkb:SETDB1
HP1 proteins KRAB domain-containing zinc finger proteins |
| gptkbp:involvedIn |
gene silencing
DNA damage response heterochromatin formation |
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:19q13.43
|
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:postTranslationalModification |
phosphorylation
SUMOylation |
| gptkbp:species |
gptkb:human
gptkb:mouse right |
| gptkbp:UniProtID |
Q13263
|
| gptkbp:bfsParent |
gptkb:ATM_kinase
|
| gptkbp:bfsLayer |
7
|