|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:activatedBy
|
Toll-like receptor signaling
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
rheumatoid arthritis
inflammatory bowel disease
|
|
gptkbp:contains
|
DNA-binding domain
IRF association domain
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
gptkb:Interferon_regulatory_factor_5_protein
|
|
gptkbp:Entrez_Gene_ID
|
3663
ENSG00000140968
|
|
gptkbp:expressedIn
|
immune cells
|
|
gptkbp:fullName
|
gptkb:Interferon_regulatory_factor_5
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
6120
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Irf5
|
|
gptkbp:involvedIn
|
innate immune response
regulation of interferon genes
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
|
|
gptkbp:location
|
gptkb:7q32
|
|
gptkbp:OMIM
|
607218
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:phosphorylates
|
gptkb:IKKε
gptkb:TBK1
|
|
gptkbp:regulates
|
type I interferon production
pro-inflammatory cytokine expression
|
|
gptkbp:UniProtID
|
Q13568
|
|
gptkbp:bfsParent
|
gptkb:IRF5
|
|
gptkbp:bfsLayer
|
8
|