IKKε

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName IKBKE protein
IKK epsilon
IKK-e
gptkbp:associatedWith gptkb:cancer
autoimmune diseases
viral infection response
gptkbp:discoveredIn 1999
gptkbp:encodedBy IKBKE gene
gptkbp:enzymeClassification serine/threonine-protein kinase
gptkbp:fullName Inhibitor of nuclear factor kappa-B kinase subunit epsilon
gptkbp:function immune response modulation
regulation of NF-κB signaling pathway
gptkbp:gene IKBKE
https://www.w3.org/2000/01/rdf-schema#label IKKε
gptkbp:locatedOnChromosome 17q24.3
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:memberOf IKK family
gptkbp:molecularWeight approximately 80 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:phosphorylates gptkb:IRF3
gptkb:IRF7
NF-κB inhibitor alpha
gptkbp:regulates type I interferon production
antiviral signaling pathways
gptkbp:relatedTo inflammation
innate immunity
gptkbp:UniProtID Q14164
gptkbp:bfsParent gptkb:BX-795
gptkbp:bfsLayer 7