Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:alternativeName |
IKBKE protein
IKK epsilon IKK-e |
| gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases viral infection response |
| gptkbp:discoveredIn |
1999
|
| gptkbp:encodedBy |
IKBKE gene
|
| gptkbp:enzymeClassification |
serine/threonine-protein kinase
|
| gptkbp:fullName |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
|
| gptkbp:function |
immune response modulation
regulation of NF-κB signaling pathway |
| gptkbp:gene |
IKBKE
|
| gptkbp:locatedOnChromosome |
17q24.3
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:memberOf |
IKK family
|
| gptkbp:molecularWeight |
approximately 80 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
gptkb:IRF3
gptkb:IRF7 NF-κB inhibitor alpha |
| gptkbp:regulates |
type I interferon production
antiviral signaling pathways |
| gptkbp:relatedTo |
inflammation
innate immunity |
| gptkbp:UniProtID |
Q14164
|
| gptkbp:bfsParent |
gptkb:BX-795
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
IKKε
|