Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
gptkbp:alternativeName |
IKBKE protein
IKK epsilon IKK-e |
gptkbp:associatedWith |
gptkb:cancer
autoimmune diseases viral infection response |
gptkbp:discoveredIn |
1999
|
gptkbp:encodedBy |
IKBKE gene
|
gptkbp:enzymeClassification |
serine/threonine-protein kinase
|
gptkbp:fullName |
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
|
gptkbp:function |
immune response modulation
regulation of NF-κB signaling pathway |
gptkbp:gene |
IKBKE
|
https://www.w3.org/2000/01/rdf-schema#label |
IKKε
|
gptkbp:locatedOnChromosome |
17q24.3
|
gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
gptkbp:memberOf |
IKK family
|
gptkbp:molecularWeight |
approximately 80 kDa
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:phosphorylates |
gptkb:IRF3
gptkb:IRF7 NF-κB inhibitor alpha |
gptkbp:regulates |
type I interferon production
antiviral signaling pathways |
gptkbp:relatedTo |
inflammation
innate immunity |
gptkbp:UniProtID |
Q14164
|
gptkbp:bfsParent |
gptkb:BX-795
|
gptkbp:bfsLayer |
7
|