Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
rheumatoid arthritis inflammatory bowel disease |
| gptkbp:encodes |
gptkb:Interferon_regulatory_factor_5_protein
|
| gptkbp:Entrez_Gene_ID |
3663
|
| gptkbp:expressedIn |
immune cells
|
| gptkbp:fullName |
gptkb:Interferon_regulatory_factor_5
|
| gptkbp:function |
immune response modulation
regulation of interferon and cytokine gene expression |
| gptkbp:HGNC_ID |
6120
|
| https://www.w3.org/2000/01/rdf-schema#label |
IRF5
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7
gptkb:7q32 |
| gptkbp:mutationAssociatedWith |
autoimmune diseases
|
| gptkbp:orthologInMouse |
gptkb:Irf5
|
| gptkbp:proteinFamily |
gptkb:interferon_regulatory_factor_family
|
| gptkbp:regulates |
pro-inflammatory cytokines
type I interferon production |
| gptkbp:UniProtID |
Q13568
|
| gptkbp:bfsParent |
gptkb:HotSpot_Therapeutics
|
| gptkbp:bfsLayer |
7
|