Interferon regulatory factor 5
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
transcription factor |
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:systemic_lupus_erythematosus
rheumatoid arthritis inflammatory bowel disease |
| gptkbp:discoveredIn |
1999
|
| gptkbp:encodedBy |
IRF5 gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of immune response
regulation of interferon expression |
| gptkbp:GO_term |
GO:0003700
GO:0006355 |
| https://www.w3.org/2000/01/rdf-schema#label |
Interferon regulatory factor 5
|
| gptkbp:involvedIn |
inflammatory response
innate immune response |
| gptkbp:locatedIn |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:7q32
|
| gptkbp:memberOf |
gptkb:interferon_regulatory_factor_family
|
| gptkbp:molecularWeight |
56 kDa
|
| gptkbp:orthologIn |
gptkb:mouse
right |
| gptkbp:PDB |
2O61
|
| gptkbp:phosphorylates |
Serine 425
|
| gptkbp:regulates |
pro-inflammatory cytokines
type I interferon genes |
| gptkbp:UniProtID |
Q13568
|
| gptkbp:bfsParent |
gptkb:IRF5
|
| gptkbp:bfsLayer |
8
|