Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
gptkbp:binds |
gptkb:interleukin-5
|
gptkbp:expressedIn |
gptkb:basophils
gptkb:mast_cells gptkb:eosinophils |
gptkbp:function |
mediates effects of interleukin-5
|
gptkbp:gene_encoding_alpha_subunit |
IL5RA
|
gptkbp:gene_encoding_beta_subunit |
CSF2RB
|
https://www.w3.org/2000/01/rdf-schema#label |
Interleukin-5 receptor
|
gptkbp:involves |
asthma
allergic inflammation |
gptkbp:location |
gptkb:cell_membrane
|
gptkbp:OMIM |
147851
|
gptkbp:signal_transduction |
gptkb:MAPK_pathway
gptkb:JAK-STAT_pathway |
gptkbp:subunit |
CSF2RB
IL5RA |
gptkbp:targetOfDrug |
gptkb:benralizumab
gptkb:mepolizumab gptkb:reslizumab |
gptkbp:UniProt_ID_(alpha_subunit) |
Q01344
|
gptkbp:UniProt_ID_(beta_subunit) |
P32927
|
gptkbp:bfsParent |
gptkb:Interleukin-5
|
gptkbp:bfsLayer |
7
|