Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
cytokine |
gptkbp:discoveredBy |
1980s
|
gptkbp:Entrez_Gene_ID |
gptkb:IL5
|
gptkbp:function |
stimulates growth and differentiation of eosinophils
promotes activation of eosinophils stimulates B cell growth enhances immunoglobulin secretion |
gptkbp:gene |
gptkb:IL5
|
gptkbp:HGNC_ID |
6026
|
https://www.w3.org/2000/01/rdf-schema#label |
Interleukin-5
|
gptkbp:involves |
asthma
eosinophilia allergic diseases |
gptkbp:locatedOnChromosome |
gptkb:chromosome_5_(human)
|
gptkbp:molecularWeight |
~26 kDa
|
gptkbp:OMIM |
147850
|
gptkbp:producedBy |
gptkb:mast_cells
gptkb:T_helper_2_cells gptkb:eosinophils |
gptkbp:recipient |
gptkb:Interleukin-5_receptor
|
gptkbp:structure |
homodimer
|
gptkbp:targetOfDrug |
gptkb:benralizumab
gptkb:mepolizumab gptkb:reslizumab |
gptkbp:UniProtID |
P05113
|
gptkbp:bfsParent |
gptkb:IL5
|
gptkbp:bfsLayer |
6
|