Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:cancer
growth disorders |
| gptkbp:biologicalProcess |
apoptosis
cell differentiation cell proliferation insulin-like growth factor binding |
| gptkbp:discoveredBy |
Shimasaki et al.
|
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodes |
gptkb:Insulin-like_growth_factor-binding_protein_3
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000146674
3486 |
| gptkbp:expressedIn |
gptkb:plasma
liver |
| gptkbp:function |
apoptosis regulation
modulation of cell growth regulation of insulin-like growth factor (IGF) availability |
| gptkbp:HGNC_ID |
HGNC:5462
|
| https://www.w3.org/2000/01/rdf-schema#label |
IGFBP3 gene
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7
7p13-p12 |
| gptkbp:mutationAssociatedWith |
growth hormone insensitivity
|
| gptkbp:OMIM |
146732
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:product |
IGFBP-3
|
| gptkbp:regulates |
gptkb:IGF-II
gptkb:IGF-I |
| gptkbp:UniProtID |
P17936
|
| gptkbp:bfsParent |
gptkb:IGFBP3
|
| gptkbp:bfsLayer |
7
|