Insulin-like growth factor-binding protein 3
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:abbreviation |
IGFBP-3
|
gptkbp:alternativeName |
IBP3
IGF-binding protein 3 |
gptkbp:binds |
gptkb:insulin-like_growth_factor_II
insulin-like growth factor I |
gptkbp:encodedBy |
gptkb:IGFBP3_gene
|
gptkbp:Entrez_Gene_ID |
3486
|
gptkbp:expressedIn |
gptkb:kidney
liver breast tissue |
gptkbp:foundIn |
gptkb:human
gptkb:plasma |
gptkbp:hasRefSeqID |
gptkb:NP_000588
|
https://www.w3.org/2000/01/rdf-schema#label |
Insulin-like growth factor-binding protein 3
|
gptkbp:involvedIn |
apoptosis
cell growth regulation |
gptkbp:locatedOnChromosome |
7p12-p13
|
gptkbp:modulatedBy |
IGF signaling
|
gptkbp:molecularWeight |
~28-40 kDa
|
gptkbp:PDB |
1B1C
|
gptkbp:regulates |
IGF bioavailability
|
gptkbp:significance |
insulin resistance
growth disorders cancer biomarker |
gptkbp:UniProtID |
P17936
|
gptkbp:bfsParent |
gptkb:IGFBP3
|
gptkbp:bfsLayer |
7
|