Human immunodeficiency virus type 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:virus
gptkbp:abbreviation	gptkb:HIV-1
gptkbp:associatedWith	HIV infection
gptkbp:Baltimore_classification	gptkb:Group_VI
gptkbp:biosafetyLevel	3
gptkbp:cause	acquired immunodeficiency syndrome
gptkbp:coReceptor	gptkb:CCR5 gptkb:CXCR4
gptkbp:discoveredBy	gptkb:Luc_Montagnier gptkb:Françoise_Barré-Sinoussi
gptkbp:discoveredIn	1983
gptkbp:entryReceptor	gptkb:CD4
gptkbp:enveloped	true
gptkbp:family	gptkb:Retroviridae
gptkbp:firstIsolatedFrom	patient with lymphadenopathy
gptkbp:genomeType	single-stranded RNA
gptkbp:genus	gptkb:Lentivirus
gptkbp:hostedBy	gptkb:human
https://www.w3.org/2000/01/rdf-schema#label	Human immunodeficiency virus type 1
gptkbp:notable_for	env tat pol gag rev nef vif vpr vpu
gptkbp:notableFor	gptkb:gp120 gptkb:gp41 gptkb:integrase gptkb:protease reverse transcriptase
gptkbp:origin	non-human primates
gptkbp:pandemic	true
gptkbp:primaryTargetCell	gptkb:dendritic_cell gptkb:CD4+_T_cell macrophage
gptkbp:regionOfOrigin	gptkb:Central_Africa
gptkbp:relatedTo	Human immunodeficiency virus type 2
gptkbp:replicationSite	gptkb:nucleus gptkb:cytoplasm
gptkbp:structure	icosahedral
gptkbp:subspecies	gptkb:HIV-1_group_M gptkb:HIV-1_group_N gptkb:HIV-1_group_O gptkb:HIV-1_group_P
gptkbp:taxonRank	11709
gptkbp:transmissionRoute	sharing needles blood transfusion mother-to-child sexual contact
gptkbp:treatment	antiretroviral therapy
gptkbp:UNIPROTOrganismID	11676
gptkbp:vaccineAvailable	false
gptkbp:bfsParent	gptkb:HIV-1_integrase
gptkbp:bfsLayer	7