Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hemoglobin
|
| gptkbp:aminoAcidChange |
glutamic acid to lysine at position 6
|
| gptkbp:associatedWith |
Hemoglobin C disease
Hemoglobin C trait |
| gptkbp:discoveredBy |
gptkb:James_V._Neel
|
| gptkbp:discoveredIn |
1950
|
| gptkbp:effectOnRedCells |
mild hemolytic anemia in homozygotes
target cells on blood smear |
| gptkbp:electrophoresisPattern |
migrates differently from HbA and HbS
|
| gptkbp:foundIn |
humans
|
| gptkbp:fullName |
Hemoglobin C
|
| https://www.w3.org/2000/01/rdf-schema#label |
HbC
|
| gptkbp:ICD-10_code |
D58.2
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:molecularWeight |
similar to normal hemoglobin
|
| gptkbp:mutationAssociatedWith |
gptkb:beta-globin_gene
|
| gptkbp:prevalence |
found in African Americans
most common in West Africa |
| gptkbp:resistanceToMalaria |
provides some protection against malaria
|
| gptkbp:bfsParent |
gptkb:Hemoglobin_electrophoresis
gptkb:hemoglobin_C |
| gptkbp:bfsLayer |
6
|