Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:virus
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:binds |
gptkb:PDZ_domain-containing_proteins
|
| gptkbp:encodedBy |
HPV E6 gene
|
| gptkbp:foundIn |
gptkb:human_papillomavirus
|
| gptkbp:function |
oncoprotein
|
| https://www.w3.org/2000/01/rdf-schema#label |
HPV E6 protein
|
| gptkbp:inhibitedBy |
apoptosis
DNA damage response |
| gptkbp:interactsWith |
gptkb:p53_protein
gptkb:E6AP_ubiquitin_ligase |
| gptkbp:involves |
head and neck cancers
anogenital cancers |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
approximately 18 kDa
|
| gptkbp:presentIn |
gptkb:HPV16
gptkb:HPV18 gptkb:high-risk_HPV_types |
| gptkbp:promotion |
degradation of p53
|
| gptkbp:regulates |
cell cycle
|
| gptkbp:role |
cellular transformation
|
| gptkbp:bfsParent |
gptkb:E6-AP
gptkb:E6-associated_protein gptkb:E6AP |
| gptkbp:bfsLayer |
8
|