Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:E6-AP
gptkb:UBE3A |
| gptkbp:discoveredBy |
Huibregtse JM et al.
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
gptkb:UBE3A_gene
|
| gptkbp:enzymeCommissionNumber |
EC 6.3.2.19
|
| gptkbp:function |
gptkb:E3_ubiquitin-protein_ligase
|
| gptkbp:GO_term |
protein binding
protein ubiquitination ubiquitin-protein transferase activity |
| gptkbp:interactsWith |
gptkb:p53_protein
gptkb:HPV_E6_protein |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_15q11-q13
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:postTranslationalModification |
ubiquitination
|
| gptkbp:role |
gptkb:cancer
gptkb:Angelman_syndrome |
| gptkbp:UniProtID |
gptkb:Q05086
|
| gptkbp:bfsParent |
gptkb:UBE3A
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
E6-associated protein
|