|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CYP2D
gptkb:CYP2D6P
gptkb:CYP2D7AP
gptkb:P450DB1
gptkb:CYP2D7
gptkb:CYP2D7P
gptkb:CPD6
gptkb:CYP2D7BP
gptkb:CYP2D8P
|
|
gptkbp:approvalYear
|
1986-12-01
|
|
gptkbp:approvedBy
|
gptkb:cytochrome_P450_family_2_subfamily_D_member_6
|
|
gptkbp:approvedSymbol
|
gptkb:CYP2D6
|
|
gptkbp:associatedWith
|
adverse drug reaction
poor metabolizer phenotype
antidepressant metabolism
antipsychotic metabolism
codeine toxicity
opioid metabolism
tamoxifen metabolism
|
|
gptkbp:dateModified
|
2022-03-10
|
|
gptkbp:dateNameChanged
|
1991-07-01
|
|
gptkbp:dateSymbolChanged
|
1991-07-01
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000100197
1565
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
gptkb:small_intestine
brain
liver
|
|
gptkbp:function
|
drug metabolism
oxidation of xenobiotics
hydroxylation of debrisoquine
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:2337
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
HGNC:2337
|
|
gptkbp:locatedOnChromosome
|
22
|
|
gptkbp:location
|
gptkb:22q13.2
|
|
gptkbp:locusType
|
gptkb:gene
gene with protein product
|
|
gptkbp:OMIM
|
124030
|
|
gptkbp:orthologIn
|
gptkb:mouse_Cyp2d22
gptkb:rat_Cyp2d1
|
|
gptkbp:partOf
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:previousName
|
gptkb:debrisoquine_4-hydroxylase
gptkb:cytochrome_P450,_subfamily_IID,_polypeptide_1
|
|
gptkbp:previousSymbols
|
gptkb:CYP2D
gptkb:P450DB1
|
|
gptkbp:proteinFamily
|
gptkb:CYP2_family
gptkb:cytochrome_P450
gptkb:CYP2D_subfamily
|
|
gptkbp:RefSeq
|
gptkb:NM_000106
|
|
gptkbp:symbol
|
approved
|
|
gptkbp:UniProtID
|
P10635
|
|
gptkbp:bfsParent
|
gptkb:CREID
|
|
gptkbp:bfsLayer
|
7
|