Statements (93)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Oncology
|
| gptkbp:can_detect |
immunohistochemistry
fluorescence in situ hybridization fluorescence in situ hybridization (FISH) |
| gptkbp:can_lead_to |
metastasis
|
| gptkbp:characteristic |
overexpression of the HER2 protein
overexpression of HER2 protein |
| gptkbp:diagnosis |
molecular testing
|
| https://www.w3.org/2000/01/rdf-schema#label |
HER2-positive breast cancer
|
| gptkbp:is_affected_by |
environmental factors
genetic factors |
| gptkbp:is_associated_with |
chemotherapy
increased healthcare costs poor prognosis multidisciplinary care teams patient advocacy efforts long-term follow-up care psychosocial impacts increased risk of recurrence increased risk of metastasis aggressive tumor behavior hormonal therapy resistance higher rates of metastasis |
| gptkbp:is_characterized_by |
high levels of HER2 gene amplification
|
| gptkbp:is_common_in |
older women
younger women |
| gptkbp:is_considered |
treatment guidelines
a target for immunotherapy |
| gptkbp:is_discussed_in |
patient education materials
|
| gptkbp:is_evaluated_by |
clinical assessment
clinical assessments biopsy patient-reported outcomes biomarker testing pathological assessment radiological assessment HER2 testing |
| gptkbp:is_informed_by |
genomic profiling
|
| gptkbp:is_linked_to |
clinical outcomes
poor prognosis survivorship issues emotional support needs quality of life considerations increased tumor aggressiveness tumor grade family history of breast cancer lymph node involvement higher risk of recurrence hormonal receptor status recurrence risk stratification cardiotoxicity from treatment inflammatory breast cancer psychosocial impacts on patients |
| gptkbp:is_managed_by |
oncologists
multidisciplinary care team |
| gptkbp:is_monitored_by |
imaging studies
regular imaging tests |
| gptkbp:is_part_of |
breast cancer research
breast cancer awareness initiatives breast cancer support groups breast cancer research funding breast cancer awareness campaigns breast cancer treatment guidelines personalized medicine approaches breast cancer research initiatives breast cancer survivorship programs oncology studies breast cancer treatment protocols breast cancer advocacy efforts breast cancer clinical pathways breast cancer patient care breast cancer patient support groups |
| gptkbp:is_studied_for |
biomarker discovery
new treatment options |
| gptkbp:is_studied_in |
clinical trials
epidemiological research |
| gptkbp:occurs_in |
other breast cancer subtypes
|
| gptkbp:prevention |
lifestyle changes
|
| gptkbp:scientific_classification |
subtype of breast cancer
|
| gptkbp:treatment |
gptkb:pertuzumab
gptkb:neratinib gptkb:surgery gptkb:trastuzumab gptkb:ado-trastuzumab_emtansine gptkb:lapatinib targeted therapies radiation therapy chemotherapy hormonal therapy neoadjuvant therapy endocrine therapy |
| gptkbp:bfsParent |
gptkb:Herceptin
|
| gptkbp:bfsLayer |
5
|