invasive lobular carcinoma

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:breast_cancer_subtype
gptkbp:accountsFor 10-15% of breast cancers
gptkbp:alsoKnownAs gptkb:ILC
gptkbp:associatedWith loss of E-cadherin expression
gptkbp:canMetastasizeTo gptkb:meninges
gastrointestinal tract
ovaries
peritoneum
gptkbp:characterizedBy single-file pattern of tumor cells
gptkbp:diagnosedBy histopathology
gptkbp:firstDescribed 1941
Foote and Stewart
gptkbp:mayPresentWith ill-defined mass
subtle thickening of breast
gptkbp:oftenExpresses estrogen receptor
progesterone receptor
gptkbp:originatedIn lobules of the breast
gptkbp:prognosis similar to invasive ductal carcinoma
gptkbp:rarelyExpresses HER2
gptkbp:riskFactor hormone replacement therapy
family history of breast cancer
female gender
increasing age
gptkbp:treatment gptkb:radiation_therapy
surgery
chemotherapy
hormonal therapy
gptkbp:bfsParent gptkb:HER2-positive_breast_cancer
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label invasive lobular carcinoma