fluorescence in situ hybridization
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
molecular biology technique
|
| gptkbp:abbreviation |
gptkb:FISH
|
| gptkbp:alternativeTo |
gptkb:Southern_blot
chromogenic in situ hybridization |
| gptkbp:appliesTo |
cells
tissue sections chromosome spreads |
| gptkbp:canBe |
environmental microbiology
bacterial identification viral detection plant cytogenetics animal cytogenetics |
| gptkbp:detects |
aneuploidy
chromosomal translocations microdeletions gene amplifications |
| gptkbp:developedBy |
1980s
|
| https://www.w3.org/2000/01/rdf-schema#label |
fluorescence in situ hybridization
|
| gptkbp:relatedTo |
cancer diagnosis
prenatal diagnosis genetic diagnostics |
| gptkbp:requires |
washing steps
counterstaining denaturation of DNA hybridization of probe |
| gptkbp:usedFor |
gene expression analysis
chromosome mapping detecting specific DNA sequences identifying chromosomal abnormalities |
| gptkbp:uses |
fluorescent probes
|
| gptkbp:visualizes |
fluorescence microscopy
|
| gptkbp:bfsParent |
gptkb:HER2-positive_breast_cancer
|
| gptkbp:bfsLayer |
7
|