HER2-enriched

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf breast cancer subtype
gptkbp:associatedWith aggressive tumor behavior
poor prognosis (without targeted therapy)
gptkbp:characteristic high HER2 expression
low estrogen receptor expression
low progesterone receptor expression
gptkbp:commonIn younger women
gptkbp:compatibleWith basal-like
luminal A
luminal B
gptkbp:definedIn gene expression profiling
https://www.w3.org/2000/01/rdf-schema#label HER2-enriched
gptkbp:isFrequently node positive at diagnosis
gptkbp:isIdentifiedBy PAM50 assay
gptkbp:isLessLikelyToExpress hormone receptors
gptkbp:subspecies gptkb:cancer
gptkbp:treatment gptkb:pertuzumab
gptkb:trastuzumab
gptkb:lapatinib
chemotherapy
HER2-targeted therapy
gptkbp:bfsParent gptkb:HER2-positive_breast_cancer
gptkbp:bfsLayer 7