Growth Differentiation Factor 2

URI: https://gptkb.org/entity/Growth_Differentiation_Factor_2
GPTKB entity
Statements (34)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:gene
gptkbp:alsoKnownAs gptkb:BMP9
gptkb:GDF2
gptkbp:associatedWith gptkb:hereditary_hemorrhagic_telangiectasia
gptkbp:discoveredBy gptkb:TGF-beta_research_community
gptkbp:encodedBy gptkb:GDF2_gene
gptkbp:Entrez_Gene_ID 2658
gptkbp:expressedIn liver
vascular endothelium
gptkbp:firstDescribed 1999
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function angiogenesis
regulation of embryonic development
bone morphogenesis
gptkbp:geneType protein-coding
https://www.w3.org/2000/01/rdf-schema#label Growth Differentiation Factor 2
gptkbp:locatedOnChromosome gptkb:chromosome_10q11.22
gptkbp:memberOf gptkb:TGF-beta_superfamily
gptkbp:molecularWeight 42 kDa (precursor)
gptkbp:OMIM 605120
gptkbp:orthologIn gptkb:Mus_musculus
gptkb:BMP10
gptkb:Rattus_norvegicus
gptkbp:pathway gptkb:SMAD_pathway
gptkbp:PDB gptkb:4YCG
gptkbp:recipient gptkb:ALK1
gptkb:ActRIIB
gptkbp:regulates iron metabolism
endothelial cell proliferation
gptkbp:structure secreted protein
gptkbp:UniProtID Q9UK05
gptkbp:bfsParent gptkb:GDF2
gptkbp:bfsLayer 6