Glycogen synthase kinase 3 alpha

URI: https://gptkb.org/entity/Glycogen_synthase_kinase_3_alpha
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName GSK-3A
GSK3 alpha
gptkbp:associatedWith gptkb:Alzheimer's_disease
gptkb:diabetes_mellitus
bipolar disorder
gptkbp:enzymeCommissionNumber EC 2.7.11.26
gptkbp:function serine/threonine protein kinase
phosphorylation of glycogen synthase
gptkbp:gene gptkb:GSK3A
https://www.w3.org/2000/01/rdf-schema#label Glycogen synthase kinase 3 alpha
gptkbp:involves gptkb:Wnt_signaling_pathway
glycogen metabolism
insulin signaling pathway
gptkbp:length 483
gptkbp:locatedOnChromosome 19q13.2
gptkbp:location gptkb:nucleus
gptkb:cytoplasm
gptkbp:molecularWeight 51 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB gptkb:1Q4L
gptkbp:phosphorylates gptkb:glycogen_synthase
gptkb:tau_protein
gptkb:beta-catenin
gptkbp:postTranslationalModification phosphorylation
acetylation
gptkbp:regulates activated by phosphorylation
inhibited by insulin
gptkbp:relatedTo gptkb:Glycogen_synthase_kinase_3_beta
gptkbp:UniProtID gptkb:P49840
gptkbp:bfsParent gptkb:GSK3α
gptkbp:bfsLayer 7