|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:GLP-1_receptor
GLP-1R
|
|
gptkbp:associatedWith
|
gptkb:insulinoma
gptkb:type_2_diabetes_mellitus
obesity
|
|
gptkbp:biologicalProcess
|
regulation of appetite
regulation of insulin secretion
G protein-coupled peptide receptor activity
regulation of gastric emptying
|
|
gptkbp:discoveredBy
|
1992
|
|
gptkbp:encodes
|
gptkb:GLP-1_receptor
|
|
gptkbp:enemyOf
|
gptkb:albiglutide
gptkb:exenatide
gptkb:liraglutide
gptkb:semaglutide
gptkb:dulaglutide
exendin 9-39
|
|
gptkbp:Entrez_Gene_ID
|
2740
ENSG00000112164
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:kidney
brain
heart
gastrointestinal tract
pancreatic beta cells
|
|
gptkbp:fullName
|
Glucagon-like peptide-1 receptor
|
|
gptkbp:function
|
mediates effects of GLP-1
receptor for glucagon-like peptide-1
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:4324
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GLP1R
|
|
gptkbp:length
|
463
|
|
gptkbp:locatedOnChromosome
|
6
|
|
gptkbp:location
|
gptkb:6p21.2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Glp1r
|
|
gptkbp:PDB
|
5VAI
6B3J
6LN2
6X18
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:signal_transduction
|
gptkb:cAMP_pathway
Gs protein activation
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:UniProtID
|
P43220
|
|
gptkbp:bfsParent
|
gptkb:GLP-1_receptor
|
|
gptkbp:bfsLayer
|
8
|