|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CXCL4
|
|
gptkbp:associatedWith
|
gptkb:heparin-induced_thrombocytopenia
autoimmune disorders
thrombosis
|
|
gptkbp:binds
|
gptkb:heparin
glycosaminoglycans
|
|
gptkbp:category
|
cytokine
secreted protein
inflammatory mediator
chemokine (CXC family)
|
|
gptkbp:discoveredBy
|
S. J. Shulman
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:expressedIn
|
gptkb:megakaryocytes
|
|
gptkbp:foundIn
|
platelets
|
|
gptkbp:fullName
|
Platelet Factor 4
|
|
gptkbp:function
|
cytokine
inhibits angiogenesis
neutralizes heparin
|
|
gptkbp:gene
|
PF4 gene
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PF4
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_4
4q12-q21
|
|
gptkbp:mainTerminal
|
gptkb:GO:0005576
gptkb:GO:0005125
GO:0008009
|
|
gptkbp:molecularWeight
|
7.8 kDa
|
|
gptkbp:orthologIn
|
gptkb:dog
gptkb:livestock
gptkb:meat
gptkb:mouse
right
|
|
gptkbp:PDB
|
1F9Q
|
|
gptkbp:relatedTo
|
gptkb:heparin-induced_thrombocytopenia
|
|
gptkbp:sequence
|
70 amino acids
|
|
gptkbp:significance
|
autoantibody target in HIT
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:UniProtID
|
P02776
|
|
gptkbp:bfsParent
|
gptkb:GATA1
|
|
gptkbp:bfsLayer
|
7
|