Erythroid transcription factor

URI: https://gptkb.org/entity/Erythroid_transcription_factor
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs GATA-1
gptkbp:binds GATA DNA sequence
gptkbp:discoveredBy gptkb:Stuart_Orkin
gptkbp:discoveredIn 1989
gptkbp:domain zinc finger domain
gptkbp:encodedBy GATA1 gene
gptkbp:expressedIn gptkb:megakaryocytes
erythroid cells
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function regulation of erythroid cell differentiation
transcriptional activation of erythroid-specific genes
gptkbp:gene gptkb:GATA1
https://www.w3.org/2000/01/rdf-schema#label Erythroid transcription factor
gptkbp:interactsWith gptkb:CBP/p300
gptkb:TAL1_protein
FOG1 protein
LDB1 protein
gptkbp:locatedOnChromosome gptkb:Xp11.23
gptkbp:molecularWeight ~50 kDa
gptkbp:mutationAssociatedWith gptkb:X-linked_dyserythropoietic_anemia_and_thrombocytopenia
gptkbp:OMIM 305371
gptkbp:regulates gptkb:KLF1_gene
hemoglobin gene expression
AHSP gene
ALAS2 gene
EPOR gene
FOG1 gene
gptkbp:requires erythropoiesis
megakaryopoiesis
gptkbp:UniProtID P15976
gptkbp:bfsParent gptkb:GATA1
gptkbp:bfsLayer 7