Forkhead box O transcription factors
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:FOXO
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:diabetes aging longevity |
| gptkbp:discoveredBy |
1990s
|
| gptkbp:domain |
forkhead DNA-binding domain
|
| gptkbp:foundIn |
animals
humans |
| gptkbp:function |
cell cycle regulation
oxidative stress response apoptosis regulation metabolism regulation transcription regulation |
| https://www.w3.org/2000/01/rdf-schema#label |
Forkhead box O transcription factors
|
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:member |
gptkb:FOXO1
gptkb:FOXO3 gptkb:FOXO4 gptkb:FOXO6 |
| gptkbp:orthologIn |
gptkb:DAF-16_(C._elegans)
|
| gptkbp:proteinFamily |
gptkb:Forkhead_box_family
|
| gptkbp:regulates |
gptkb:PI3K/AKT_pathway
growth factors phosphorylation insulin signaling ubiquitination acetylation |
| gptkbp:bfsParent |
gptkb:FOXO_transcription_factors
|
| gptkbp:bfsLayer |
6
|