|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:FOXO3
gptkb:FOXO3a
|
|
gptkbp:associatedWith
|
gptkb:cancer
neurodegenerative diseases
human longevity
|
|
gptkbp:discoveredIn
|
1999
|
|
gptkbp:encodedBy
|
FOXO3 gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000118689
2309
|
|
gptkbp:expressedIn
|
many human tissues
|
|
gptkbp:function
|
gptkb:transcription_factor
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:3821
|
|
gptkbp:inhibitedBy
|
insulin signaling
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:memberOf
|
Forkhead box O family
|
|
gptkbp:orthologInMouse
|
gptkb:Foxo3
|
|
gptkbp:phosphorylates
|
gptkb:AKT1
gptkb:SGK
|
|
gptkbp:regulates
|
gptkb:immune_response
apoptosis
longevity
DNA repair
lipid metabolism
metabolism
cellular senescence
mitochondrial function
angiogenesis
muscle atrophy
inflammation
cell cycle
stem cell maintenance
protein degradation
DNA damage response
autophagy
tumor suppression
oxidative stress response
insulin sensitivity
glucose homeostasis
erythropoiesis
cellular differentiation
cellular proliferation
cellular stress resistance
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
O43524
|
|
gptkbp:bfsParent
|
gptkb:FOXO3
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Forkhead box O3
|