|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD32B
|
|
gptkbp:associatedWith
|
gptkb:systemic_lupus_erythematosus
autoimmune diseases
|
|
gptkbp:binds
|
IgG Fc region
|
|
gptkbp:contains
|
ITIM motif
|
|
gptkbp:domain
|
immunoglobulin-like domain
cytoplasmic ITIM domain
|
|
gptkbp:encodedBy
|
gptkb:FCGR2B_gene
|
|
gptkbp:expressedIn
|
gptkb:B_cells
gptkb:mast_cells
dendritic cells
macrophages
monocytes
neutrophils
|
|
gptkbp:function
|
inhibitory receptor for IgG
|
|
gptkbp:gene
|
gptkb:FCGR2B
|
|
gptkbp:HGNC_ID
|
3617
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FcγRIIB
|
|
gptkbp:inhibitedBy
|
B cell activation
antibody production
|
|
gptkbp:interactsWith
|
gptkb:SHP-2
gptkb:SHP-1
|
|
gptkbp:locatedOnChromosome
|
1q23
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:memberOf
|
Fc gamma receptor family
|
|
gptkbp:modulatedBy
|
inflammatory response
|
|
gptkbp:OMIM
|
147620
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:regulates
|
immune response
allergic response
phagocytosis
antibody-dependent cellular cytotoxicity
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:UniProtID
|
P31994
|
|
gptkbp:bfsParent
|
gptkb:PTPN6
|
|
gptkbp:bfsLayer
|
7
|