|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
TLS
translocated in liposarcoma
|
|
gptkbp:associatedWith
|
amyotrophic lateral sclerosis
frontotemporal dementia
|
|
gptkbp:biologicalProcess
|
DNA repair
transcription regulation
protein binding
mRNA splicing
nucleic acid binding
|
|
gptkbp:chromosomeArm
|
p
|
|
gptkbp:discoveredBy
|
gptkb:Christopher_D._A._Panagopoulos
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
gptkb:FUS_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000089280
2521
|
|
gptkbp:expressedIn
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:formsFusionGeneWith
|
gptkb:CHOP
gptkb:ATF1
gptkb:CREB3L1
gptkb:CREB3L2
gptkb:DDIT3
gptkb:ERG
gptkb:EWSR1
gptkb:TAF15
gptkb:PRF1
|
|
gptkbp:fullName
|
gptkb:Fused_in_Sarcoma
|
|
gptkbp:function
|
DNA repair
RNA binding
transcription regulation
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
gptkb:FUS
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FUS gene
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
16
|
|
gptkbp:mutationAssociatedWith
|
nonsense
missense
neurodegeneration
frameshift
splice site
|
|
gptkbp:OMIM
|
137070
|
|
gptkbp:orthologInMouse
|
Fus
|
|
gptkbp:postTranslationalModification
|
phosphorylation
methylation
ubiquitination
|
|
gptkbp:proteinFamily
|
gptkb:FET_family
gptkb:Arg-Gly-Gly_(RGG)_box
zinc finger domain
RNA recognition motif
glycine-rich region
prion-like domain
|
|
gptkbp:relatedTo
|
gptkb:rhabdomyosarcoma
gptkb:Ewing_sarcoma
liposarcoma
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:stress_granules
|
|
gptkbp:UniProtID
|
gptkb:P35637
|
|
gptkbp:bfsParent
|
gptkb:FUS_protein
gptkb:Fused_in_Sarcoma
|
|
gptkbp:bfsLayer
|
6
|