stress granules

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf Cell
gptkbp:associatedWith translation arrest
gptkbp:composedOf proteins
mRNAs
gptkbp:contains RNA-binding proteins
translation initiation factors
gptkbp:dissolved stress relief
gptkbp:dynamic yes
gptkbp:firstDescribed 1999
gptkbp:formed cellular stress
gptkbp:formedBy liquid-liquid phase separation
gptkbp:foundIn eukaryotic cells
https://www.w3.org/2000/01/rdf-schema#label stress granules
gptkbp:involves gptkb:Alzheimer's_disease
gptkb:ALS
neurodegenerative diseases
gptkbp:regulates protein translation
mRNA metabolism
gptkbp:relatedTo gptkb:P-bodies
gptkbp:size 0.1–2 μm
gptkbp:visualizes fluorescence microscopy
gptkbp:bfsParent gptkb:P-bodies
gptkb:TAR_DNA-binding_protein_43
gptkbp:bfsLayer 6