|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
TLS
translocated in liposarcoma
|
|
gptkbp:associatedWith
|
amyotrophic lateral sclerosis
frontotemporal dementia
|
|
gptkbp:discoveredBy
|
Crozat et al.
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:domain
|
gptkb:RRM_domain
zinc finger domain
glycine-rich region
|
|
gptkbp:encodedBy
|
gptkb:FUS_gene
|
|
gptkbp:Entrez_Gene_ID
|
2521
|
|
gptkbp:formsFusionGeneWith
|
gptkb:CHOP
gptkb:ATF1
gptkb:CREB3L1
gptkb:CREB3L2
gptkb:DDIT3
gptkb:ERG
gptkb:EWSR1
gptkb:NR4A3
gptkb:TAF15
|
|
gptkbp:function
|
gptkb:RNA-binding_protein
DNA repair
transcription regulation
|
|
gptkbp:HGNC_ID
|
4011
|
|
gptkbp:interactsWith
|
gptkb:RNA_polymerase_II
gptkb:EWSR1
gptkb:TAF15
|
|
gptkbp:involvedIn
|
DNA damage response
mRNA splicing
transcription-coupled DNA repair
|
|
gptkbp:locatedOnChromosome
|
gptkb:16p11.2
|
|
gptkbp:molecularWeight
|
53 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:familial_ALS
gptkb:sporadic_ALS
gptkb:FTD
|
|
gptkbp:OMIM
|
137070
|
|
gptkbp:orthologInMouse
|
Fus
|
|
gptkbp:relatedTo
|
gptkb:rhabdomyosarcoma
gptkb:Ewing_sarcoma
gptkb:myxoid_liposarcoma
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:symbol
|
gptkb:FUS
|
|
gptkbp:UniProtID
|
gptkb:P35637
|
|
gptkbp:bfsParent
|
gptkb:FUS
|
|
gptkbp:bfsLayer
|
5
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fused in Sarcoma
|