|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
FK506-binding protein 5
FKBP5
|
|
gptkbp:associatedWith
|
gptkb:depression
psychiatric disorders
stress-related disorders
|
|
gptkbp:binds
|
gptkb:rapamycin
FK506 (tacrolimus)
|
|
gptkbp:encodedBy
|
FKBP5 gene
|
|
gptkbp:Entrez_Gene_ID
|
2289
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:adrenal_gland
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
heart
liver
spleen
colon
pancreas
peripheral blood leukocytes
|
|
gptkbp:function
|
immunophilin
peptidyl-prolyl cis-trans isomerase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FKBP51
|
|
gptkbp:interactsWith
|
gptkb:androgen_receptor
glucocorticoid receptor
progesterone receptor
heat shock protein 90 (Hsp90)
|
|
gptkbp:involvedIn
|
stress response
glucocorticoid receptor signaling
regulation of steroid receptor complexes
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
gptkb:6p21.31
|
|
gptkbp:molecularWeight
|
51 kDa
|
|
gptkbp:OMIM
|
602623
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
1KT0
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:regulates
|
glucocorticoid sensitivity
stress hormone response
|
|
gptkbp:UniProtID
|
Q13451
|
|
gptkbp:bfsParent
|
gptkb:FKBP12
|
|
gptkbp:bfsLayer
|
7
|