Extracellular signal-regulated kinases (ERKs)
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
gptkb:ERKs
|
| gptkbp:activatedBy |
gptkb:MAPK/ERK_kinase_(MEK)
phosphorylation |
| gptkbp:alias |
gptkb:ERK1
gptkb:ERK2 |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
regulate cell differentiation
regulate cell proliferation regulate cell survival |
| gptkbp:gene |
gptkb:MAPK1
gptkb:MAPK3 |
| https://www.w3.org/2000/01/rdf-schema#label |
Extracellular signal-regulated kinases (ERKs)
|
| gptkbp:inhibitedBy |
gptkb:PD98059
gptkb:U0126 |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:memberOf |
serine/threonine protein kinases
|
| gptkbp:partOf |
gptkb:mitogen-activated_protein_kinase_(MAPK)_pathway
|
| gptkbp:phosphorylates |
transcription factors
cytoskeletal proteins other kinases |
| gptkbp:relatedTo |
gptkb:cancer
developmental biology cell signaling |
| gptkbp:structure |
contains kinase domain
|
| gptkbp:bfsParent |
gptkb:MAPK/ERK_signaling_pathway
|
| gptkbp:bfsLayer |
6
|