Ewing sarcoma breakpoint region 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:gene
gptkbp:alternativeName	gptkb:EWS gptkb:EWS_RNA-binding_protein_1
gptkbp:associatedWith	gptkb:Ewing_sarcoma gptkb:myxoid_liposarcoma gptkb:desmoplastic_small_round_cell_tumor
gptkbp:discoveredBy	1992
gptkbp:encodes	RNA-binding protein EWS
gptkbp:Entrez_Gene_ID	gptkb:ENSG00000084674 2130
gptkbp:expressedIn	gptkb:skeletal_muscle gptkb:testis brain various tissues
gptkbp:function	RNA processing transcriptional regulation
gptkbp:fusionPartners	gptkb:WT1 gptkb:ATF1 gptkb:DDIT3 gptkb:ERG gptkb:NR4A3 gptkb:POU5F1 gptkb:FLI1
gptkbp:geneType	protein coding
gptkbp:hasTranscriptVariant	yes
gptkbp:HGNC_ID	HGNC:3508
gptkbp:interactsWith	gptkb:SR_proteins gptkb:RNA_polymerase_II gptkb:FUS gptkb:CREB-binding_protein gptkb:TAF15
gptkbp:length	656 amino acids
gptkbp:locatedOnChromosome	chromosome 22 22q12.2
gptkbp:molecularWeight	68 kDa
gptkbp:mutationAssociatedWith	oncogenic fusion proteins
gptkbp:OMIM	133450
gptkbp:orthologInMouse	Ewsr1
gptkbp:splicing_variant	multiple isoforms
gptkbp:subcellularLocation	gptkb:nucleus gptkb:cytoplasm
gptkbp:symbol	gptkb:EWSR1
gptkbp:UniProtID	Q01844
gptkbp:bfsParent	gptkb:EWSR1
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Ewing sarcoma breakpoint region 1